The second and third of these images I also posted last year to mark Good Friday and I am doing so again as I think them amongst the most profound amomgst so many depictions over the centuries.
The Descent from the Cross
Rogier van der Weyden circa 1435
Hugo van der Goes circa 1470
Joseph of Arimathea (behind Jesus) and Nicodemus (at Jesus' left)
Kunsthistorisches Museum Vienna